米兰-欧盟评估非转基因塔宾曲霉菌株NL151生产的三酰甘油脂肪酶的安全性

欧盟评估非转基因塔宾曲霉菌株NL151出产的三酰甘油脂肪酶的平安性时候：2024-10-11 13:32来历：食物火伴网作者： 泽夕 焦点提醒：2024年10月10日，欧盟食物平安局就一种食物酶三酰甘油脂肪酶（triacylglycerol lipase）的平安性评价发布定见。 食物火伴网讯 2024年10月10日，欧盟食物平安局就一种食物酶三酰甘油脂肪酶（triacylglycerol lipase）的平安性评价发布定见。 据领会，这类食物酶是由非转基因塔宾曲霉菌株NL151出产的，旨在用在6种食物出产进程。 颠末评估，专家小组认为，在预期的利用前提下，不克不及解除经由过程饮食接触引发过敏反映的风险，但这类环境产生的可能性很低。按照所供给的数据，小组得出结论，该食物酶在预期的利用前提下不会引发平安问题。部门原文报导以下： The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase; EC 3.1.1.3) is produced with the non-genetically modified Aspergillus tubingensis strain NL151 by Shin Nihon Chemical Co., Ltd. The food enzyme was free from viable cells of the production organism. It is intended to be used in six food manufacturing processes. Dietary exposure was estimated to be up to 0.278 mg total organic solids (TOS)/kg body weight (bw) per day in European populations. Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 1669 mg TOS/kg bw per day, the highest dose tested, which when compared with the estimated dietary exposure, resulted in a margin of exposure of at least 6004. A search for homology of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel considered that, the risk of allergic reactions upon dietary exposure cannot be excluded, but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use. 本文由食物火伴网食物资讯中间编纂，供网友参考，有任何疑问，请联系news@foodmate.net。